Reading assignments include scientific articles, class handouts, online resources, and sections from the required text. Assignments for this course also used to include several readings from the MIT Biology Hypertextbook, but these have been removed as that site is no longer active. At this time there are no plans to re-present the materials.
Freeman, Scott. Biological Science. Upper Saddle River, NJ: Prentice Hall, 2002. ISBN: 9780130819239.
|2||Biochemistry 1||Chapter 2|
|6||Genetics 1||Chapter 10, pp. 194-201|
|7||Genetics 2||Chapter 10, pp. 201-214|
|8||Genetics 3||Chapter 8.2 (pp. 159-164) and pp. 176-191|
|9||Human Genetics||Chapter 17.2, pp. 339-342|
|10||Molecular Biology 1||pp. 59-61, Chapter 11, 12|
|11||Molecular Biology 2||Chapter 13, pp. 252-259|
|Quiz 1, Lectures 1-10|
|12||Molecular Biology 3||Chapter 13, pp. 259-271, 244-246|
|13||Gene Regulation||Chapter 14|
|14||Protein Localization||Protein Trafficking. pp. 95-103|
|15-18||Recombinant DNA 1|
Recombinant DNA 2
Recombinant DNA 3
Recombinant DNA 4
|Spencer, Charlotte A. Genetic Testimony: A Guide to Forensic DNA Profiling. San Francisco, CA: Benjamin Cummings, 2003. ISBN: 9780131423381.|
|Quiz 2, Lectures 11-17|
|19||Cell Cycle/Signaling||pp. 164-168, 864-867|
|20||Cancer||Weinberg, R. A. "How Cancer Arises." Sci Am. 275, no. 3 (September 1996): 62-70.|
———. "Finding the Anti-oncogene." Sci Am. 259, no. 3 (September 1988): 44-51.
|21||Virology/Tumor Viruses||Chapter 26, pp. 501-507|
Humoral Immunology (PDF)
|24||AIDS||Chapter 26.2, pp. 507-516|
|25||Genomics||Lander, E. S., and R. A. Weinberg. "Genomics: Journey to the Center of Biology." Science 287, no. 5459 (March 10, 2000): 1777-82.|
|Quiz 3, Lectures 18-24|
|26||Nervous System 1||Chapter 42, pp. 806-817|
|27||Nervous System 2||Chapter 42, pp. 817-822|
|28||Nervous System 3||Chapter 42, pp. 822-827|
|29-30||Stem Cells/Cloning 1|
Stem Cells/Cloning 2
|pp. 346, 406-407, 364-367|
Essay on p. 826
Growth and Differentiation, a Case of Hematopoiesis (PDF)
|31||Molecular Medicine 1||NCI Gleevec Article|
|32||Molecular Evolution||Genetics and Geneology, Why Y?|
The Family Lemba (PBS Nova)
The Family Cohanim (PBS Nova)
Did Thomas Jefferson Father Slave Children? (PBS Nova)
|33||Molecular Medicine 2||Essay: pp. 782-783|
The Cholesterol Quartet
|34||Human Polymorphisms and Cancer Classification|
|35||Future of Biology|
This course features a complete set of video lectures by Professor Eric Lander, Director of the Broad Institute at MIT and a principal leader of the Human Genome Project and Professor Robert A. Weinberg, winner of the 1997 National Medal of Science.
Education development efforts for these introductory biology courses are one of many activities conducted by the HHMI Education Group at MIT. This group focuses on curriculum development work for creating teaching tools in undergraduate biology courses.
The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological function at the molecular level is particularly emphasized and covers the structure and regulation of genes, as well as, the structure and synthesis of proteins, how these molecules are integrated into cells, and how these cells are integrated into multicellular systems and organisms. In addition, each version of the subject has its own distinctive material.
7.012 focuses on the exploration of current research in cell biology, immunology, neurobiology, genomics, and molecular medicine.
The study materials, problem sets, and quiz materials used during Fall 2004 for 7.012 include contributions from past instructors, teaching assistants, and other members of the MIT Biology Department affiliated with course #7.012. Since the following works have evolved over a period of many years, no single source can be attributed.